Table I.

β-catenin target genes identified in the present study.

	CRISPR-Cas9		RNAi
Symbol	PCC	P-value	PCC	P-value	Chromosomal location	Description
ABHD10	0.430	0.025	−0.477	0.016	3q13.2	Abhydrolase domain containing 10
AFG3L2	−0.427	0.026	0.371	0.012	18p11.21	AFG3 like matrix AAA peptidase subunit 2
COPS8	−0.465	0.014	0.336	0.024	2q37.3	COP9 signalosome subunit 8
DHX15	−0.587	0.001	−0.440	0.003	4p15.2	DEAH-box helicase 15
GMPS	0.496	0.009	0.349	0.019	3q25.31	Guanine monophosphate synthase
IARS2	−0.421	0.029	−0.341	0.022	1q41	Isoleucyl-tRNA synthetase 2, mitochondrial
MED28	−0.473	0.013	−0.421	0.004	4p15.32	Mediator complex subunit 28
MYBa	0.484	0.011	0.462	0.001	6q23.3	MYB proto-oncogene, transcription factor
RPL35	0.455	0.017	0.559	<0.001	9q33.3	Ribosomal protein L35
RRAD	0.559	0.002	0.487	0.001	16q22.1	RRAD, Ras related glycolysis inhibitor and calcium channel regulator
SRSF10	−0.537	0.004	−0.383	0.010	1p36.11	Serine and arginine rich splicing factor 10
SRSF6	0.420	0.029	−0.366	0.013	20q13.11	Serine and arginine rich splicing factor 6
WWP2	0.423	0.028	0.373	0.013	16q22.1	WW domain containing E3 ubiquitin protein ligase 2

P-values indicate the significance level of the PCC value.

^aPreviously reported as known β-catenin target (51). Cas9, CRISPR associated protein 9; PCC, Pearson correlation coefficient; RNAi, RNA interference.