Figure 4. DNLA reduced the production of Aβ by decreasing APP.

The protein expression levels of Aβ_1–42 (B), PS1 (C) and APP (D) as determined from densitometric scans of Western blots. DNLA significantly decreased the protein expression of Aβ_1–42 (35, 350, 700 ng/mL) and APP (350 ng/mL). However, DNLA did not change the protein expression of PS1. (A) Representative strips of these proteins. Data are presented as the mean ± SD (n = 4). *P < 0.05 versus the sham group.