Table 2.

Birth and infant growth outcomes by prenatal PrEP exposure

	Overall (N = 1530)		PrEP exposed (N = 206)		PrEP unexposed (N = 1324)		Unadjusted coeff. or OR (95% CI)	Adjusted coeff. or OR (95% CI)
	Mean or N (%)	95% CI	Mean or N (%)	95% CI	Mean or N (%)	95% CI
Birth outcomes
Gestational age at birth (weeks)a	38.5	38.3, 38.8	38.5	38.0, 39.0	38.6	38.3, 38.8	−0.05 (−0.49, 0.39)	0.0055 (−0.38, 0.39)
Preterm birthb	95 (6.4)	2.9, 13.6	7 (3.4)	1.9, 6.2	88 (6.9)	2.9, 15.6	0.48 (0.17, 1.38)	0.43 (0.15, 1.21)
Congenital malformationb	5 (0.3)	0.1, 1.3	0 (0.0)	–	5 (0.4)	0.1, 1.5	–	–
Birthweight (kg)a	3.3	3.3, 3.4	3.4	3.3, 3.5	3.3	3.3, 3.3	0.06 (−0.05, 0.16)	0.10* (0.0055, 0.20)
Low birthweightb	30 (2.2)	1.4, 3.3	1 (0.5)	0.1, 4.7	29 (2.5)	1.6, 3.7	0.73 (0.31, 1.73)	0.58 (0.20, 1.73)
Six week infant growth outcomes
Weight (kg)a	5.1	4.9, 5.2	5.0	4.9, 5.2	5.1	4.9, 5.2	−0.04 (−0.16, 0.07)	−0.022 (−0.19, 0.14)
Absolute weight‐for‐age z‐score (WAZ)a	0.4	0.2, 0.6	0.4	0.1, 0.6	0.4	0.2, 0.6	−0.03 (−0.21, 0.14)	0.022 (−0.18, 0.23)
Moderate‐to‐severe underweightb	31 (2.6)	1.5, 4.7	4 (2.7)	1.1, 6.5	27 (2.6)	1.4, 4.9	1.07 (0.43, 2.66)	0.64 (0.17, 2.35)
Length (cm)a	55.8	55.1, 56.5	55.8	54.8, 56.8	55.8	55.1, 56.5	−0.03 (−0.93, 0.87)	−0.27 (−1.37, 0.82)
Absolute length‐for‐age z‐score (LAZ)a	0.1	−0.3, 0.4	0.1	−0.3, 0.6	0.1	−0.3, 0.4	0.05 (−0.35, 0.45)	−0.086 (−0.60, 0.43)
Moderate‐to‐severe stuntingb	104 (8.7)	6.4, 11.8	11 (7.6)	4.1, 13.6	93 (8.9)	6.3, 12.3	0.84 (0.40, 1.75)	1.38 (0.49, 3.92)
Weight‐for‐length (WHZ) Z‐scorea	0.6	0.3, 0.9	0.6	0.1, 1.2	0.6	0.2, 0.9	0.04 (−0.38, 0.46)	0.21 (−0.18, 0.61)
Moderate‐to‐severe wastingb	88 (73)	4.7, 11.4	9 (6.3)	2.4, 15.8	79 (7.5)	4.8, 11.6	0.81 (0.36, 1.81)	0.75 (0.26, 2.18)

Adjusted for gestational age at PrEP screening and Partner HIV status.

^aCoefficient; ^bodds ratio.

*p < 0.05.