Table 4.
Multivariate analysis of parameters
| Multivariable cox regression | |||
|---|---|---|---|
| HR (95% CI) | P-value | ||
| Sex | 0.47 (0.12–1.79) | 0.27 | |
| Age | 0.98 (0.92–1.05) | 0.62 | |
| PS | 1.83 (0.93–3.62) | 0.08 | |
| Histology | Adenocarcinoma | 0.21 | |
| Squamous cell carcinoma | 0.64 (0.15–2.69) | 0.54 | |
| NSCLC | 0.28 (0.06–1.30) | 0.10 | |
| Smoking Status | Never | 0.13 | |
| Stopped over 10 years ago | 0.52 (0.05–5.67) | 0.59 | |
| Stopped between 1 and 10 years ago | 0.11 (0.01–1.48) | 0.10 | |
| Current smoker or stopped less than 1 year ago | 0.51 (0.06–4.39) | 0.54 | |
| Number of previous treatment Lines | 0.56 (0.28–1.11) | 0.09 | |
| Albumin | 0.35 (0.12–0.97) | 0.04 | |
| BMI | 1.19 (0.93–1.51) | 0.16 | |
| SMI | 0.75 (0.29–1.94) | 0.55 | |
| FFMI | 2.17 (0.09–50.55) | 0.63 | |
| FMI | 0.99 (0.68–1.46) | 0.97 | |
| Weight change | 0.35 (0.18–0.66) | 0.001 | |
Note: Weight change units of 10% change were utilized for cox regression analysis.
Abbreviations: HR, hazard ratio; CI, confidence interval; PS, performance status.