Fig. 5. HMT enzymatic activity in breast cancer cells is down-regulated by natural compounds:
A. Combinatorial SFN and WA down-regulate HMT activity with SFN being most effective in MCF-7 breast cancer cells. B. Histone methyltransferase activity is down-regulated by SFN and WA in MDA-MB-231(n=3; p < 0.05*).