Table 1.
Synthetic polymers used in this study and their characteristics.
| Polymer | Product name | Grade | Dissolution pH threshold | % ionisable groups | M.W. (g/mol) | Manufacturer/supplier |
|---|---|---|---|---|---|---|
| Methacrylic acid copolymer | EUDRAGIT® | Dimethyl amino ethyl[1] | Evonik GmbH, Darmstadt, Germany | |||
| E100 | ≤5.0 | 20.8–25.5 | 47,000 | |||
| Methacrylic acid[2] | ||||||
| L100 | ≥6.0 | 46.0–50.6 | 125,000 | |||
| S100 | ≥7.0 | 27.6–30.7 | 125,000 | |||
| HPMC acetate succinate (AS) | Aqoat® | Succinoyl[3] | Shin-Etsu Chemical Co., Ltd., Japan | |||
| LF | ≥5.5 | 14.0–18.0 | 18,000 | |||
| HF | ≥6.8 | 4.0–8.0 | 18,000 | |||
| HPMC phthalate (HP) | HPMCP | Phthalyl[4] | ||||
| HP-50 | ≥5.0 | 21.0–27.0 | 78,000 | |||
| HP-55 | ≥5.5 | 27.0–35.0 | 84,000 | |||
[1]: Evonik, 2015; [2]:Evonik, 2012; [3]: Shin-Etsu, 2005; [4]: Shin-Etsu, 2002.