Figure 4.
Impacts of TNTs with periodic structures on drug release.67
Note: (A) Schematic diagram of fabricating drug-loaded p-TNT. (B) SEM images of TNTs and p-TNTs, (b1) the top surface with opening pores, (b2) the cross section of the TNT layer, (b3) the cross section of TNTs, (b4) the cross section of p-TNTs, (b5) the high-resolution image of p-TNTs indicating a reduction of internal pore dimensions. (C) In-vitro drug-release graphs comparing the release from conventional flat TNTs and p-TNTs, (c1) initial burst release in 6 hrs, (c2) total drug release until the entire amount of the drug is exhausted. Reproduced from Gulati K, Kant K, Findlay D, Losic D. Periodically tailored titania nanotubes for enhanced drug loading and releasing performances. J Mater Chem B. 2015;3(12):2553-2559, with permission of The Royal Society of Chemistry, http://dx.doi.org/10.1039/c4tb01882f.
Abbreviations: p-TNTs, TNTs with periodic structures; TNT, titanium dioxide nanotube.