Table 1.

Distribution of 597 MBC cases and 1022 male population controls according to genotype frequencies of CYP17A1 rs743572, CYP1B1 rs1056836 and rs1800440 and MBC risk estimates.

Polymorphism	Genotype	MBC cases (n = 597)		Male controls (n = 1022)		OR (95% CI)	P value
		n	%	n	%
CYP17A1 c.-34T>C	TT	190	31.8	347	33.9	Ref
rs743572	TC	301	50.4	489	47.9	1.07 (0.84–1.38)	0.57
	CC	106	17.8	186	18.2	0.90 (0.66–1.26)	0.57
	Co-dominant					0.97 (0.83–1.14)	0.71
CYP1B1 p.Leu432Val	GG	231	38.7	385	37.7	Ref
rs1056836	GC	290	48.6	482	47.1	0.94 (0.75–1.20)	0.66
	CC	76	12.7	155	15.2	0.79 (0.56–1.12)	0.19
	Co-dominant					0.91 (0.77–1.06)	0.23
CYP1B1 p.Asn453Ser	AA	365	61.2	654	64.0	Ref
rs1800440	AG	208	34.8	321	31.4	1.13 (0.89–1.43)	0.3
	GG	24	4.0	47	4.6	1.14 (0.65–1.99)	0.64
	Co-dominant					1.11 (0.91–1.34)	0.31