Table 3.
Polymorphism | Genotype | ER-positive MBC cases (n = 418) | ER-negative MBC cases (n = 30) | Chi2 P-value | ||
---|---|---|---|---|---|---|
n | % | n | % | |||
CYP17A1 c.-34T>C | TT | 125 | 29.9 | 9 | 30.0 | 0.39 |
rs743572 | TC | 211 | 50.5 | 18 | 60.0 | |
CC | 82 | 19.6 | 3 | 10.0 | ||
CYP1B1 p.Leu432Val | GG | 161 | 38.5 | 8 | 26.7 | 0.31 |
rs1056836 | GC | 205 | 49.0 | 19 | 63.3 | |
CC | 52 | 12.5 | 3 | 10.0 | ||
CYP1B1 p.Asn453Ser | AA | 261 | 62.5 | 22 | 73.3 | 0.35 |
rs1800440 | AG | 141 | 33.7 | 8 | 26.7 | |
GG | 16 | 3.8 | 0 | 0.0 |