Table 2.
MRI identification of the adenoma | SSa (P) | |||
---|---|---|---|---|
Microadenoma (n = 43) | Macroadenoma (n = 16) | No imaging data (n = 6) | ||
Mean (s.d.) | Mean (s.d.) | Mean (s.d.) | ||
Cortisol nadir (nmol/L) | 81.1b (117.0) | 254.1b (305.4) | 186.2 (342.1) | 0.016 |
Time to cortisol nadir (h) | 46.6c (28.2) | 84.3c (38.7) | 56.0 (29.7) | 0.001 |
ACTH nadir (pmol/L) | 3.1b (3.6) | 9.6b (13.4) | 2.6 (2.0) | 0.011 |
Time to ACTH nadir (h) | 46.6b (33.0) | 77.7b (38.9) | 38.0 (23.1) | 0.006 |
Last ACTH measurement (pmol/L) | 3.1b (3.5) | 9.6b (13.4) | 2.6 (2.0) | 0.010 |
Time of last ACTH measurement (h) | 130 (52) | 162 (54) | 111 (37) | 0.061 |
aSS, statistical significance (ANOVA); bSignificant differences between macroadenomas and microadenomas (Scheffe test and Bonferroni test; P < 0.05); cSignificant differences between macroadenomas and microadenomas (Scheffe test and Bonferroni test; P < 0.01).