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. 2019 May 24;1:100016. doi: 10.1016/j.ijpx.2019.100016

Table 2.

Gel point temperature (GPT) design of experiments (DoE) responses.

Run Point Randomization Factor A: NMP/water ratio % (v/v) Factor B: total poloxamer conc % (w/w) Factor C: P338/P407 ratio % (w/w) Response: GPT °C
1 Factorial 6 0/100 20 0/100 23.28
2 Factorial 10 25/75 20 0/100 22.32
3 Factorial 12 0/100 25 0/100 18.43
4 Factorial 2 25/75 25 0/100 10.06
5 Factorial 7 0/100 20 100/0 30.03
6 Factorial 3 25/75 20 100/0 36.88
7 Factorial 4 0/100 25 100/0 24.74
8 Factorial 9 25/75 25 100/0 21.12
9 Axial 13 0/100 22.5 50/50 24.91
10 Axial 15 25/75 22.5 50/50 23.53
11 Axial 14 12.5/87.5 20 50/50 30.64
12 Axial 18 12.5/87.5 25 50/50 22.27
13 Axial 17 12.5/87.5 22.5 0/100 21.11
14 Axial 16 12.5/87.5 22.5 100/0 29.93
15 Center 11 12.5/87.5 22.5 50/50 26.37
16 Center 8 12.5/87.5 22.5 50/50 25.74
17 Center 1 12.5/87.5 22.5 50/50 26.26
18 Center 5 12.5/87.5 22.5 50/50 26.30