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Formulations for gel erosion study.
| Formulation | Bedaquiline fumarate salt concentration mg/g | NMP/water ratio % (v/v) | Total poloxamer concentration % (w/w) | P338/P407 ratio % (w/w) | GPT °C |
|---|---|---|---|---|---|
| 1 | 10 | 25/75 | 23.5 | 100/0 | 26 |
| 2 | 10 | 25/75 | 20.0 | 20.4/79.6 | 26 |
| 3 | 10 | 25/75 | 20.0 | 47.7/52.3 | 30 |
| 4 | 10 | 25/75 | 21.9 | 57.3/42.7 | 26 |
