Skip to main content
. 2019 Sep 9;14(9):e0222352. doi: 10.1371/journal.pone.0222352

Fig 1. Changes in body weight, food intake, calorie intake, and tissue weight in the four experimental groups.

Fig 1

WT and CCR2 KO mice were fed HFD or RD for 10 weeks. (a) Body weight changes over time. (b) Food intake changes over time. (c) Calorie showed no significant difference among the four groups. (d) Weights of kidney, liver, WAT, pancreas, and skeletal muscle were increased by HFD. However, only liver weight was significantly decreased by CCR2 depletion in HFD KO. RD WT, Regular diet wild type; RD KO, Regular diet CCR2 knockout; HFD WT, High-fat diet wild type; HFD KO, High-fat diet CCR2 knockout; WAT, White adiposity tissue. *P < 0.05 compared to that in RD WT; #P < 0.05 compared to that in HFD WT.