Table 2. .
Characteristics of the Study population, All Six Subgroups
|
Characteristic |
Normals |
POAGS |
POAG |
PACS |
PAC |
PACG |
P Value* |
||||||
|
N
|
Value |
N |
Value |
N |
Value |
N
|
Value |
N
|
Value |
N
|
Value |
||
| CT, μm (mean [SD]) | 40 | 234 (75) | 45 | 237 (67) | 61 | 234 (86) | 23 | 319 (114) | 30 | 357 (138) | 26 | 272 (87) | <0.0001 |
| AL, mm (median [IQ]) | 37 | 23.8 (1.8) | 45 | 24.3 (1.8) | 60 | 24.2 (2.0) | 23 | 22.1 (2.0) | 30 | 22.5 (1.3) | 26 | 22.8 (1.3) | <0.0001 |
| ACD, mm (median [IQ]) | 39 | 3.36 (0.93) | 42 | 3.42 (0.69) | 59 | 3.19 (0.57) | 23 | 2.74 (0.53) | 30 | 2.76 (0.53) | 25 | 2.84 (1.22) | <0.0001 |
| VF MD, dB (median [IQ]) | NA | 45 | −0.85 (2.02) | 60 | −4.89 (8.27) | 23 | −0.54 (1.88) | 30 | −0.59 (1.44) | 26 | −4.76 (10.48) | <0.0001 | |
| CCT, μm (mean [SD]) | 37 | 555 (33) | 45 | 557 (41) | 59 | 536 (40) | 23 | 581 (28) | 30 | 556 (32) | 26 | 536 (41) | <0.0001 |
| Previous glaucoma surgery (N [%]) | NA | 45 | 1 (2) | 61 | 13 (21) | 23 | 0 (0) | 30 | 1 (3) | 26 | 8 (31) | 0.0002 | |
| Ethnicity (N [%]) | |||||||||||||
| White non-Hispanic | 40 | 32 (80) | 45 | 37 (82) | 61 | 44 (72) | 23 | 17 (74) | 30 | 26 (87) | 26 | 10 (38) | 0.002† |
| White-Hispanic | 1 (2) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 1 (4) | |||||||
| African American | 4 (10) | 5 (11) | 15 (25) | 5 (22) | 2 (7) | 11 (42) | |||||||
| Asian | 3 (8) | 3 (7) | 2 (3) | 1 (4) | 2 (7) | 3 (12) | |||||||
| Other | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 1 (4) | |||||||
| IOP, mm Hg (median [IQ]) | 37 | 14.0 (5.0) | 45 | 16.0 (5.5) | 61 | 13.5 (5.5) | 23 | 16.0 (5.0) | 30 | 15.0 (7.0) | 26 | 14.2 (8.5) | 0.01 |
| DPP, mm Hg (median [IQ]) | 37 | 63.0 (14.0) | 44 | 59.5 (14.2) | 59 | 52.5 (13.0) | 23 | 56.0 (7.5) | 30 | 58.5 (13.5) | 25 | 55.5 (13.0) | 0.03 |
| Sex (N [%]) | |||||||||||||
| Male | 40 | 16 (40) | 45 | 19 (42) | 61 | 32 (62) | 23 | 6 (26) | 30 | 7 (23) | 26 | 9 (35) | 0.08 |
| Female | 24 (60) | 26 (58) | 29 (48) | 17 (74) | 23 (77) | 17 (65) | |||||||
| Age, y (median [IQ]) | 40 | 65.7 (15.1) | 45 | 66.6 (14.2) | 61 | 68.5 (10.2) | 23 | 66.1 (18.1) | 30 | 63.3 (19.6) | 26 | 71.8 (14.4) | 0.11 |
| MPP, mm Hg (median [IQ]) | 37 | 82.0 (15.3) | 44 | 76.3 (13.5) | 59 | 79.3 (14.5) | 23 | 71.3 (13.0) | 30 | 75.5 (8.2) | 25 | 75.5 (12.7) | 0.13 |
| Pseudophakic (N [%]) | NA | 45 | 9 (20) | 61 | 11 (18) | 22 | 2 (9) | 30 | 4 (13) | 26 | 9 (35) | 0.18 | |
*
Significance of differences among subgroups: χ2 test, ANOVA, or Kruskal-Wallis test.
†
White versus nonwhite.