Table 3. Alternative scale factors used to simulate pharmacological manipulation with Moxifloxacin.
IC50 = 93.041 μM Hill slope = 0.6 |
Moxifloxacin | IC50 = 382.337 μM Hill slope = 1.1 |
IC50 = 50.321 μM Hill slope = 1 |
---|---|---|---|
Scale factor gKr | Concentration [μM] | Scale factor gNaL | Scale factor gKs |
0.34 | 277.4 | 0.59 | 0.15 |
0.51 | 86.2 | 0.84 | 0.37 |
0.81 | 8.32 | 0.985 | 0.86 |
0.87 | 3.76 | 0.994 | 0.930 |