Fig. 2. Circulating concentrations of the 11-oxygenated derivatives of androstenedione in adult animals across different species.
LC-MS/MS was utilized to measure the serum concentrations of 11OHA4 and 11KA4 in 17 species. Males and females were pooled. In addition to all primates, guinea pigs exhibited significant serum amounts of both 11OHA4 and 11KA4. Data are denoted as mean ± SEM. Steroid concentrations are expressed in nmol/L (nM). 11OHA4, 11β-hydroxyandrostenedione; 11KA4, 11-ketoandrostenedione.
