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. 2019 Sep 4;39(36):7155–7172. doi: 10.1523/JNEUROSCI.0220-19.2019

Table 5.

Age-related changes in amygdala activity in the PNC sample using coordinates from previous studiesa

Region Emotion F(1,754) p Effect size
Right amygdala in Gee et al. (2013) Neutral 1.121 0.290 −0.040
Fear 0.228 0.633 0.018
Anger 0.174 0.677 −0.016
Sad 1.965 0.161 0.052
Happy 0.109 0.741 −0.012
Left amygdala in Kujawa et al. (2016)b Neutral 0.953 0.329 0.036
Fear 12.617 0.0004 0.132
Anger 1.844 0.175 0.051
Sad 15.140 0.0001 0.144
Happy 9.020 0.003 0.111
Right amygdala in Kujawa et al. (2016)b Neutral 0.566 0.452 0.028
Fear 2.650 0.104 0.061
Anger 0.123 0.726 0.013
Sad 2.801 0.095 0.063
Happy 0.726 0.394 0.032
Left amygdala (AAL) in Wu et al. (2016)b Neutral 1.583 0.209 0.047
Fear 15.796 7.73e-05 0.147
Anger 4.571 0.033 0.080
Sad 20.755 6.08e-06 0.168
Happy 10.009 0.002 0.117
Right amygdala (AAL) in Wu et al. (2016)b Neutral 0.277 0.599 0.020
Fear 5.741 0.017 0.089
Anger 1.946 0.163 0.052
Sad 5.784 0.016 0.089
Happy 1.553 0.213 0.046

aEffect size is measured by the standardized partial coefficient of the age term. AAL, Automated anatomical labeling; ↓, developmental decreases in amygdala with mPFC was reported in the cited study. AAL indicates that the amygdala ROI was derived based on AAL atlas.

bNo significant developmental changes were found in the cited study.