Figure 4.

Transcriptomic and translatomic differences between the TG and DRG of mice. A, B, Volcano plots showing genes that are enriched in the DRG or TG in the whole tissue transcriptome (input) or in the TRAP-seq sample (Nav1.8-TRAP) with genes highlighted in the text labeled (yellow dots). C, GO term analysis of the TRAP-seq-enriched mRNAs in DRG or TG using EnrichR (adjusted p value < 0.05) shows an enrichment in AMPK-related genes in the DRGs, whereas mTOR-related genes are highly translated in the TG. D, Heatmaps showing the expression level of enriched mRNAs (input) and enriched translated mRNAs (Nav1.8 TRAP) in both tissues showing discordance between the transcriptome and translatome mRNA levels.