Skip to main content
. 2019 Sep 9;8:e48417. doi: 10.7554/eLife.48417

Figure 8. Virally transduced neurons show no major changes of basic properties.

Figure 8.

(A) GFP positive neurons were visualized according to their GFP fluorescence (A2) and targeted for whole-cell patch clamp recordings (A1), scale bars 10µm. (B) Overview image of a double positive pyramidal neuron (GFP and Biocytin) after whole cell recording and post-hoc staining, scale bar 500 µm; (C1–C3) and in detail, scale bar 20 µm. (C) Example of a representative regular firing pattern of a GFP positive pyramidal neuron (+200 pA). (D) Quantification of basic properties of GFP negative and GFP positive human pyramidal neurons. (E) Example of a GFP positive fast spiking interneuron. (E1-E3) GFP signal, biocytin filling and merge of the same neuron, scale bar 20 µm. (F) Quantification of basic properties of GFP negative and GFP positive human interneurons, *p<0.05, Mann Whitney test.