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. 2019 Aug 16;12(8):e007547. doi: 10.1161/CIRCINTERVENTIONS.118.007547

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© 2019 The Authors.

Circulation: Cardiovascular Interventions is published on behalf of the American Heart Association, Inc., by Wolters Kluwer Health, Inc. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution, and reproduction in any medium, provided that the original work is properly cited.

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Figure 2. — Structural and functional coronary and myocardial changes during the cardiac cycle and vasodilator stress. A, Diagrammatic representation of the extravascular forces and intraluminal pressures affecting myocardial layers, demonstrating greater subendocardial contraction during systole. B, Perfusion quantification map in a patient with AS (rows from top to bottom are basal, mid, and apical slices, respectively, with stress, rest, and myocardial perfusion reserve [MPR] in columns left to right). Global endocardial-epicardial gradient 0.9, MPR 2.0. P_INTRAMURAL indicates intramural pressure; P_LUMEN, pressure in the left ventricular lumen; and P_PERICARDIUM, pressure in the pericardial space. Adapted from Duncker and Bache and Bell and Fox^25,26 with permission. Copyright ©2008, The American Physiological Society.