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Collagen gel contraction assay. Collagen gels containing cardiac fibroblasts were polymerized and either remained attached to the walls of a 24-well plate (constrained; top row) or physically detached (free-floating in culture media; bottom row). The left column has images of gels taken 4 h after polymerization and the middle column are images after 24 h. Schematic in the right column illustrates a side-on view of the collagen gels within the well
