Skip to main content
. Author manuscript; available in PMC: 2019 Sep 9.
Published in final edited form as: Sci Transl Med. 2019 Feb 27;11(481):eaat2004. doi: 10.1126/scitranslmed.aat2004

Fig. 3. SHM frequencies in B cell clones with members that bind TT in antibody phage display.

Fig. 3.

scFv antibody phage display libraries were generated from IgH, Igκ, and Igλ transcripts from subjects 2072 and 2074. Members of the TT-specific clonal lineages were identified from phage clones in the total IgH repertoire sequence data sets generated for each antibody isotype from the PBMCs of the children, and the isotype and SHM percentages in the IGHV gene of all clone members were plotted. Each dot represents a read from a TT-binding clone member, with each clone plotted in a different color.