Table 2:

Associations between Developmental Disorders and Allergic Disease among Children in NHANES 2005–2010

	n	Crude OR (95% CI)	p value	Adjusted OR* (95% CI)	p value*
Asthma	7335	1.65 (1.28 – 2.12)	<0.001	1.51 (1.12 – 2.02)	0.007
Current asthma	7322	1.80 (1.37 – 2.37)	<0.001	1.40 (0.98 – 1.99)	0.06
Recent attack	6874	2.12 (1.52 – 2.95)	<0.001	1.61 (1.09 – 2.36)	0.02
ED/urgent care	6480	2.41 (1.43 – 4.05)	0.001	1.41 (0.74 – 2.71)	0.28
Wheezing	10179	1.66 (1.27 – 2.18)	<0.001	1.49 (1.11 – 2.01)	0.01
Allergic rhinitis	10169	1.48 (0.96 – 2.28)	0.08	1.45 (0.95 – 2.21)	0.08
Self-reported FA§	5915	1.12 (0.71 – 1.78)	0.62	1.08 (0.70 – 1.66)	0.71
Peanut		1.72 (0.53 – 5.60)	0.35	2.07 (0.69 – 6.20)	0.19
Milk		1.75 (0.97 – 3.17)	0.06	2.33 (1.21 – 4.49)	0.01
Wheat		0.47 (0.06 – 3.72)	0.46	0.69 (0.09 – 5.46)	0.72
Egg		2.61 (0.87 – 7.85)	0.09	3.52 (1.06 – 11.7)	0.04
Soy		2.26 (0.14 – 36.0)	0.55	3.34 (0.37 – 30.0)	0.27
Fish		3.20 (0.83 – 12.3)	0.09	0.53 (0.11 – 2.63)	0.43
Shellfish		1.06 (0.83 – 5.87)	0.11	0.79 (0.33 – 1.91)	0.59
Corn		2.16 (0.35 – 13.3)	0.40	1.96 (0.49 – 7.83)	0.33
Tree nuts		2.00 (0.50 – 8.09)	0.32	2.06 (0.45 – 9.47)	0.34
Other		0.39 (0.24 – 0.65)	0.001	0.34 (0.19 – 0.61)	0.001
Sensitization (IgE)†
Peanut	3309	1.92 (1.21 – 3.07)	0.01	1.83 (1.05 – 3.18)	0.04
Milk	3264	0.94 (0.48 – 1.84)	0.85	1.04 (0.57 – 1.90)	0.89
Egg	3299	0.70 (0.41 – 1.19)	0.17	0.81 (0.43 – 1.53)	0.50
Shrimp	2382	0.51 (0.27 – 0.97)	0.04	0.44 (0.22 – 0.88)	0.02
Aeroallergens	3319	0.98 (0.71 – 1.34)	0.88	0.92 (0.64 – 1.33)	0.64

^*Models adjusted for sex, age, race/ethnicity, household income, and low birth weight

^§NHANES 2007–2010; FA, food allergy

^†NHANES 2005–2006