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. 2019 Sep 6;11:646–653. doi: 10.1016/j.dadm.2019.07.004

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© 2019 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 3 — Association between plasma lipocalin-2 and neuropsychological measures. All subjects regardless of preclinical AD status were included in the analysis. (A-D) Plasma lipocalin-2 levels were not associated with MMSE (age- and sex-adjusted, beta coefficient –0.0629, P = .42), WMS-R-LM I (age- and sex-adjusted, beta coefficient −0.0142, P = .46), WMS-R-LM II (age- and sex-adjusted, beta coefficient –0.0186, P = .831), and Trail Making A scores (age- and sex-adjusted, beta coefficient 0.145, P = .14). (E) Plasma lipocalin-2 levels were associated with Trail Making B scores (age- and sex-adjusted, beta coefficient 0.228, P = .014). Scatterplots with individual values and unadjusted regression lines are shown. Abbreviations: AD, Alzheimer's disease; MMSE, Mini–Mental State Examination; WMS-R-LM, Wechsler Memory Scale–Revised, Logical Memory.