Table 3.

Nanoemulsion suggested by “Design Expert” software at independent variables and their responses.

Formulation code	Independent variables			Dependent variables
	Coded factors			Observed responses			Predicted responses
	X1	X2	X3	Y1	Y2	Y3	Y1	Y2	Y3
ENE1	5	30	40	209.47 ± 12.78	0.511 ± 0.029	71.10 ± 1.59	212.87	0.513	69.66
ENE2	10	30	40	223.99 ± 13.87	0.449 ± 0.028	64.33 ± 1.51	219.17	0.461	66.09
ENE3	5	40	40	280.99 ± 15.89	0.459 ± 0.029	60.97 ± 1.49	278.51	0.474	60.10
ENE4	10	40	40	313.01 ± 18.27	0.572 ± 0.034	58.63 ± 1.48	318.68	0.581	57.70
ENE5	5.5	35.5	59	79.92 ± 6.33	0.229 ± 0.019	98.88 ± 1.31	78.65	0.237	99.75
ENE6	10	30	60	141.01 ± 9.83	0.264 ± 0.026	81.44 ± 1.01	148.75	0.271	81.88
ENE7	5	40	60	98.32 ± 8.16	0.281 ± 0.027	96.46 ± 1.16	108.92	0.280	93.69
ENE8	10	40	60	149.62 ± 8.64	0.404 ± 0.035	90.10 ± 0.98	151.50	0.411	90.40
Axial Points
ENE9	3.2955	35	50	56.23 ± 5.10	0.249 ± 0.019	95.98 ± 1.17	52.48	0.251	98.26
ENE10	11.7045	35	50	97.32 ± 7.12	0.319 ± 0.021	93.69 ± 1.03	93.58	0.318	92.48
ENE11	7.5	26.5910	50	269.27 ± 16.15	0.459 ± 0.030	60.18 ± 1.03	268.13	0.465	59.89
ENE12	7.5	43.4090	50	332.27 ± 19.61	0.558 ± 0.039	56.66 ± 1.16	325.64	0.550	59.02
ENE13	7.5	35	33.1821	310.98 ± 16.45	0.602 ± 0.049	53.27 ± 0.98	312.42	0.587	54.06
ENE14	7.5	35	66.8179	119.44 ± 9.62	0.261 ± 0.029	94.89 ± 1.31	110.59	0.265	95.59
Centre Points
ENE15	7.5	35	50	130.97 ± 7.69	0.3180 ± 0.018	90.15 ± 1.10	136.13	0.320	90.02
ENE16	7.5	35	50	135.92 ± 8.95	0.3200 ± 0.017	90.15 ± 0.96	136.13	0.320	90.02
ENE17	7.5	35	50	135.92 ± 8.95	0.3200 ± 0.017	90.15 ± 0.96	136.13	0.320	90.02