. 2019 May 3;26(10):3250–3259. doi: 10.1245/s10434-019-07344-5

Table 4.

Summary of trigger and progression, by surveillance group

		Tape measurement	BIS
	N = 508	N = 245	N = 263
Follow-up (months)^a	17.8 (13–23)	17.6 (13–23)	18.2 (13–23)
Progressed before intervention^b	10 (2.0)	6 (2.4)	4 (1.5)

	N = 498	N = 239	N = 259	p-Value
Sample for potential trigger
Triggered^b	109 (21.9)	68 (28.5)	41 (15.8)	0.001
Median months to trigger^a	4.0 (1.0–11.2)	2.8 (0.6–5.6)	9.5 (2.3–10.1)	0.002
Progression^b	12 (11.0)	10 (14.7)	2 (4.9)	0.130
Median time, months [trigger to progression]^c	6.0 (0.8, 16.9)	6.0 (1.4, 16.9)	6.7 (0.8, 12.5)	0.389

Bold values indicate statistical significance (p < 0.05)

Months from randomization to last assessment for these analyses

Progression to criteria for being off-study without the interim intervention (subclinical) threshold

BIS bioimpedance spectroscopy, IQR interquartile range

^aMedian (IQR)

^bn (%)

^cMedian (minimum, maximum)