Fig. 10. Transplantation of OEC-converted neurons into injured adult spinal cord.
a Schematic diagram showing the experimental procedure of stereotactical injection of induced cells into crushed spinal cord. b Survival of GFP-labeled induced cells at one month post injection (mpi). c–e Immunohistochemical analysis of OEC-derived neurons by staining with antibodies against Tuj1, Map2, and synapsin-1 (SYN1) in the spinal cord of NOD-SCID mice. Scale bar, 100 μm for b; 50 μm for c–e