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. 2019 Sep 9;10:4075. doi: 10.1038/s41467-019-11875-6

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — Graphic representation of operational and logistic parameters for hMOR ligands populating different clusters. Operational transduction coefficients (Log(τ/KA)) and logistic E_max values derived from concentration response curves generated by hMORs at ten different biosensors were represented as radial graphs. Each radius corresponds to the magnitude of Log(τ/KA) or E_max values. Transduction coefficients are in logarithmic scale, E_max values were normalized to maximal Met-ENK response, and are presented on linear scale. Source data provided in Supplementary Data 1