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. 2019 Sep 3;13:918. doi: 10.3389/fnins.2019.00918

TABLE 2.

Action potential characterization for wild-type (WT) and mutant Nav1.9 channels in small DRG neurons.

Input Current
resistance threshold Amplitude Half-width
Nav1.9 RMP (mV) (MΩ) (pA) (mV) (ms) AHP (mV)
WT n = 39 −52.2 ± 1.1 574 ± 37 189 ± 21 117 ± 2.3 6.84 ± 0.41 −62.6 ± 0.77
N816K n = 43 −45.1 ± 1.2∗∗∗ 571 ± 34 105 ± 13∗∗∗ 111 ± 2.0 7.59 ± 0.38 −60.7 ± 1.0
p-value 2.58e−5 0.945 7.70e−4 0.0650 0.183 0.135

∗∗∗p < 0.001 versus WT channels.