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. 2019 Sep 3;6:79. doi: 10.3389/fmolb.2019.00079

Figure 1.

Figure 1

A diagram to show how resection influences repair pathway choice. Approximately 80% of DSBs are repaired by classical NHEJ which does not require resection. aNHEJ or MMEJ requires minimal resection to expose regions of microhomology. Long range resection is required for the major HDR pathways gene conversion (GC) and single-strand annealing (SSA). Key proteins in each pathway are given in red.