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. 2019 Sep 3;10:951. doi: 10.3389/fphar.2019.00951

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Copyright © 2019 Yang, Zang, Shan, Guo, Wu, Wang and Wang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Anti-glioma effects of D14 and D31 on C6 glioma model in rats. (A), Representative HE staining result of the implanted gliomas (×100); (B) Representative immunohistochemical staining for GFAP in the gliomas tissues (×100); (C) Representative MRI images of brains of glioma-bearing rats with or without drugs treatment. (D) Tumor volumes of glioma-bearing rats with or without drugs treatment. The results are expressed as mean values ± SD. *P < 0.05, compared to the control group. (E) Body weight changes of Wistar rats before and after drugs treatment.