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. 2019 Sep 3;10:951. doi: 10.3389/fphar.2019.00951

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Copyright © 2019 Yang, Zang, Shan, Guo, Wu, Wang and Wang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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D31 induced ROS generation without affecting NADPH oxidase activity. (A), Effects of D31 on ROS production analyzed by flow cytometry in C6 (a) and U87 (b) cells; (B), Mean fluorescent intensity of C6 (a) and U87 (b) cells after D31 treatment; (C), Effects of apocynin and D31 on NADPH oxidase activities in C6 (a) and U87 (b) cells. The results are expressed as mean values ± SD. *P< 0.05 compared with control.