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. 2019 Sep 3;10:946. doi: 10.3389/fphar.2019.00946

Figure 10.

Figure 10

In vivo toxicity and biodistribution of Fe(PIP)3SO4 after 72 h. (A) In vivo biodistribution of Fe(PIP)3SO4 in major organs after i.v. administration for 72 h. The yellow and green histograms represent the baseline and Fe(PIP)3SO4 groups, respectively. Values are presented as means ± SD in triplicate. (B) Body weight growth treated with Fe(PIP)3SO4, cisplatin, and TMZ after 72 h. (C) H&E staining of heart, liver, spleen, lung, kidney, and brain in NIH mice after treatments with Fe(PIP)3SO4, cisplatin, and TMZ for 72 h.