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. 2019 Sep 3;10:946. doi: 10.3389/fphar.2019.00946

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Copyright © 2019 Zhu, Dai, He, Xu and Chen

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Inhibition of TrxR activity triggered by Fe(PIP)₃SO₄. (A) Inhibitory efficacy of cellular TrxR activity in U87 cells triggered by Fe(PIP)₃SO₄ in 50 min. (B) The most remarkable variation of cellular TrxR activity in U87 cells induced by Fe(PIP)₃SO₄ at 13-min time point. Values are presented as means ± SD in triplicate. Significant difference between the treatment and control groups is indicated at the P<0.05 (*) or P<0.01 (**) level.