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. 2019 Sep 3;10:1993. doi: 10.3389/fmicb.2019.01993

TABLE 4.

Comparison of the sensitivity, specificity, positive predict value, negative predict value, and accuracy among four methods in patients with definite TBM.

Methods Sensitivity (%) Specificity (%) PPV (%) NPV (%) Accuracy (%)
Culture 8.33(1/12) 100(6/6) 100(1/1) 35.29(6/17) 38.89(7/18)
PCR 25(3/12) 100(6/6) 100(3/3) 40(6/15) 50(9/18)
1st AFB 33.33(4/12) 100(6/6) 100(4/4) 42.86(6/14) 55.56(10/18)
Acc AFB 66.67(8/12) 100(6/6) 100(8/8) 60(6/10) 77.78(14/18)
1st mNGS 66.67(8/12) 100(6/6) 100(8/8) 60(6/10) 77.78(14/18)

PPV, positive predict value; NPV, negative predict value; Acc, Accumulated test including the first and repeated analysis of CSF samples.