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. 2019 Aug 8;13:57–73. doi: 10.1016/j.eclinm.2019.06.011

Fig. 3.

Fig. 3

Categories of failed a) all insomnia treatments and b) pharmacologic insomnia treatments at intake.

Abbreviations: OTC — over the counter; CBT — cognitive-behavioral therapy; SSRI — selective serotonin reuptake inhibitor; SSNRI — selective serotonin and norepinephrine reuptake inhibitor.

Footnote:

aPatients suffered from insomnia for an average of 10 years and reported multiple attempts at insomnia treatment [mean 4.48 (3.61–5.34)].

bOTC supplements and herbal remedies.

cEducation from books, articles, magazines, etc.

dCBT does not refer to CBT-I. No patient was introduced to or attempted CBT-I.

eMeditation, acupuncture, other alternative therapies.

fBenzo: lorazepam, alprazolam, clonazepam, triazolam, temazepam; SSRI & SSNRI: sertraline, escitalopram, fluoxetine, duloxetine, paroxetine; OTC supplement: melatonin, 5-htp; Sedating anti-depressant: mirtazapine, doxepin, trazodone; Z drug: eszopiclone, zolpidem; Gaba agonist: gabapentin; Antihistamine: diphenhydramine, chlorpheniramine, doxylamine; Muscle relaxant: baclofen, chlorzoxazone; Illicit drugs: tetrahydrocannabinol (THC).