Table 2b.
Comparison of baseline characteristics for subjective/objective primary and secondary measures, % or mean (95% confidence interval)a, by completers (n = 40).
| Completers (n = 40) |
Intake CPAP (n = 21) |
Intake ASV (n = 19) |
p-value, g | |
|---|---|---|---|---|
| Primary measures | ||||
| ISI | 19.30 (18.40–20.20) | 19.48 (18.30–20.65) | 19.11 (17.61–20.60) | 0.683, 0.13 |
| SQ-Lik | 3.08 (2.76–3.40) | 2.95 (2.53–3.38) | 3.23 (2.70–3.75) | 0.395, 0.27 |
| SQ-Pct (%) | 52.01 (47.16–56.86) | 49.47 (42.53–56.41) | 54.82 (47.62–62.02) | 0.270, 0.35 |
| Secondary measures | ||||
| Questionnaires | ||||
| ESS | 5.70 (4.73–6.67) | 5.52 (3.89–7.16) | 5.89 (4.74–7.05) | 0.706, 0.12 |
| III | 19.20 (16.87–21.53) | 18.00 (15.23–20.77) | 20.53 (16.47–24.58) | 0.280, 0.34 |
| FSS | 40.55 (36.44–44.66) | 36.81 (30.47–43.15) | 44.68 (39.67–49.70) | 0.052, 0.62 |
| FOSQ-10 | 14.91 (14.08–15.74) | 15.12 (14.08–16.17) | 14.68 (13.27–16.09) | 0.597, 0.16 |
| QLESQ (%) | 60.22 (54.36–66.09) | 61.56 (53.58–69.55) | 58.74 (49.32–68.16) | 0.633, 0.15 |
| Sleep diary | ||||
| SOL | 58.49 (40.70–76.28) | 57.40 (29.91–84.88) | 59.69 (34.88–84.51) | 0.898, 0.04 |
| WASO | 79.33 (59.82–98.83) | 90.57 (59.83–121.30) | 66.90 (41.92–91.88) | 0.225, 0.38 |
| SE (%) | 73.95 (69.34–78.56) | 71.87 (65.48–78.25) | 76.26 (69.10–83.43) | 0.342, 0.30 |
| PSG sleep indices | ||||
| SOL | 25.32 (15.33–35.32) | 26.76 (11.77–41.75) | 23.73 (9.22–38.25) | 0.764, 0.09 |
| WASO | 71.79 (54.38–89.19) | 68.71 (40.67–96.75) | 75.18 (52.68–97.68) | 0.712, 0.12 |
| SE (%) | 76.48 (71.06–81.91) | 77.50 (68.69–86.31) | 75.36 (68.45–82.26) | 0.695, 0.12 |
| N1 (%) | 6.26 (4.14–8.38) | 7.47 (4.18–10.76) | 4.92 (2.11–7.73) | 0.230, 0.38 |
| N2 (%) | 61.05 (57.03–65.06) | 62.28 (55.70–68.85) | 59.68 (54.74–64.62) | 0.521, 0.20 |
| N3 (%) | 14.24 (11.05–17.42) | 13.19 (8.70–17.67) | 15.39 (10.47–20.32) | 0.491, 0.22 |
| REM (%) | 18.46 (15.73–21.19) | 17.07 (13.04–21.10) | 19.99 (16.07–23.90) | 0.286, 0.34 |
| REM (min) | 62.39 (50.84–73.94) | 60.89 (43.58–78.21) | 64.05 (47.27–80.84) | 0.786, 0.08 |
| PSG breathing indices | ||||
| AHI | 19.16 (13.52–24.80) | 22.83 (12.64–33.01) | 15.11 (10.69–19.52) | 0.169, 0.43b |
| CAI | 0.13 (0.02–0.24) | 0.28 (0.10–0.30)c | 0.83 (0.10–1.70)c | 0.281, 0.36 |
| RDI | 34.05 (29.26–38.84) | 38.79 (30.56–47.02) | 28.81 (24.88–32.75) | 0.033, 0.69b |
Abbreviations: ISI — Insomnia Severity Index; SQ-Lik — Sleep quality Likert scale; SQ-Pct — Sleep quality percent scale; ESS — Epworth Sleepiness Scale; III — Insomnia Impairment Index; FSS — Fatigue Severity Scale; FOSQ-10 — Functional Outcomes of Sleep Questionnaire Short Form; QLESQ — Quality of Life Enjoyment and Satisfaction Questionnaire Summary; SOL — sleep onset latency; WASO — wake after sleep onset; SE — sleep efficiency; N1 — non-REM stage 1; N2 — non-REM stage 2; N3 — non-REM stage 3; REM — rapid eye movement sleep; AHI — Apnea Hypopnea Index; RDI — Respiratory Disturbance Index.
t-test confidence interval for continuous variables.
The statistical significance and effect sizes for both AHI and RDI are not clinically relevant because in both instances they reflect patients with similar clinical severity levels of sleep-disordered breathing.
Due to high prevalence of “0s” in data, Exact Wilcoxon Sign Ranked Test was used for pseudo median and confidence intervals.