Table 3b.
Completer intake, final outcome, and change scores for subjective/objective primary and secondary measures, mean (95% confidence interval)a, for ASV.
| Intake ASV (n = 19) |
Final/exit ASV (n = 19) |
Change ASV (n = 19)b |
Within-subjects ASV; p, g | |
|---|---|---|---|---|
| Primary measures | ||||
| ISI | 19.11 (17.61–20.60) | 5.89 (4.14–7.65) | 13.21 (10.72–15.70) | < 0.0001, 2.50 |
| SQ-Lik | 3.23 (2.70–3.75) | 4.87 (4.44–5.30) | 1.65 (1.10–2.19) | < 0.0001, 1.42 |
| SQ-Pct (%) | 54.82 (47.62–62.02) | 79.14 (74.94–83.35) | 24.33 (17.99–30.66) | < 0.0001, 1.81 |
| Secondary measures | ||||
| Questionnaires | ||||
| ESS | 5.89 (4.74–7.05) | 4.74 (3.03–6.44) | 1.16 (− 0.65 to 2.97) | 0.196, 0.30 |
| III | 20.53 (16.47–24.58) | 7.63 (4.81–10.45) | 12.89 (8.63–17.16) | < 0.0001, 1.43 |
| FSS | 44.68 (39.67–49.70) | 26.58 (19.90–33.26) | 18.11 (13.10–23.11) | < 0.0001, 1.71 |
| FOSQ-10 | 14.68 (13.27–16.09) | 17.12 (15.81–18.43) | 2.44 (1.08–3.80) | 0.0014, 0.85 |
| QLESQ (%) | 58.74 (49.32–68.16) | 72.74 (65.09–80.40) | 14.00 (6.94–21.07) | 0.0006, 0.94 |
| Sleep diary | ||||
| SOL | 59.69 (34.88–84.51) | 33.94 (18.72–49.16) | 25.75 (12.67–38.83) | 0.0006, 0.93 |
| WASO | 66.90 (41.92–91.88) | 32.00 (19.31–44.68) | 34.90 (11.00–58.81) | 0.0066, 0.69 |
| SE (%) | 76.26 (69.10–83.43) | 84.73 (80.03–89.43) | 8.47 (3.36–13.57) | 0.0026, 0.78 |
| PSG sleep indices | ||||
| SOL | 23.73 (9.22–38.25) | 16.56 (8.25–24.86) | 7.17 (− 5.79 to 20.14) | 0.260, 0.26 |
| WASO | 75.18 (52.68–97.68) | 75.31 (46.10–104.51) | 0.12 (− 29.95 to 29.70) ‡ | 0.993, 0.00 |
| SE (%) | 75.36 (68.45–82.26) | 78.21 (70.72–85.70) | 2.85 (− 4.88 to 10.59) | 0.448, 0.17 |
| N1 (%) | 4.92 (2.11–7.73) | 3.57 (2.31–4.82) | 1.35 (− 0.77 to 3.47) | 0.197, 0.30 |
| N2 (%) | 59.68 (54.74–64.62) | 55.24 (46.40–64.09) | 4.44 (− 3.95 to 12.83) | 0.281, 0.25 |
| N3 (%) | 15.39 (10.47–20.32) | 21.30 (14.36–28.24) | 5.91 (5.15–12.33) | 0.069, 0.43 |
| REM (%) | 19.99 (16.07–23.90) | 19.90 (16.19–23.61) | 0.09 (− 4.29 to 4.47) ‡ | 0.966, 0.01 |
| REM (min) | 64.05 (47.27–80.84) | 67.13 (50.36–83.90) | 3.08 (− 14.26 to 20.41) | 0.713, 0.08 |
| REMCI | 17.64 (12.31–22.98) | 18.17 (13.25–23.10) | 0.53 (− 6.96 to 8.03) | 0.883, 0.03 |
| PSG breathing indices | ||||
| AHI | 15.11 (10.69–19.52) | 0.53 (0.20–9.30)c | 14.01 (9.20–18.82) | < 0.0001, 1.37 |
| CAI | 0.83 (0.10–1.70)c | 0d | 0.83 (0.1–1.70)c | 0.063c,e |
| RDI | 28.81 (24.88–32.75) | 8.81 (4.88–12.73) | 20.01 (14.46–25.55) | < 0.0001, 1.70 |
| RERAI | 13.70 (10.93–16.47) | 7.71 (4.24–11.18) | 5.99 (1.95–10.03) | < 0.0001, 0.70 |
| NSBT (%) | 56.30 (46.38–66.21) | 88.89 (83.08–94.70) | 32.60 (20.67–44.52) | < 0.0001, 1.29 |
| NSBT (min) | 175.38 (136.51–214.24) | 303.48 (259.56–347.40) | 128.11 (81.68–174.54) | < 0.0001, 1.30 |
Abbreviations: ASV — adaptive servo-ventilation; CPAP — continuous positive airway pressure; ISI — Insomnia Severity Index; SQ-Lik — Sleep quality Likert scale; SQ-Pct — Sleep quality percent scale; ESS — Epworth Sleepiness Scale; III — Insomnia Impairment Index; FSS — Fatigue Severity Scale; FOSQ-10 — Functional Outcomes of Sleep Questionnaire Short Form; QLESQ — Quality of Life Enjoyment and Satisfaction Questionnaire Summary; SOL — sleep onset latency; WASO — wake after sleep onset; SE — sleep efficiency; N1 — non-REM stage 1; N2 — non-REM stage 2; N3 — non-REM stage 3; REM — rapid eye movement sleep; REMCI — REM consolidation index; AHI — Apnea Hypopnea Index; RDI — Respiratory Disturbance Index; RERAI — Respiratory Effort-Related Arousal event Index; NSBT — normal sleep breathing time.
t-test confidence interval.
All changes are in expected direction (improvement) except those identified by ‡.
Due to high prevalence of “0s” in data, Exact Wilcoxon Sign Ranked Test.
All values were "0".
No g value reported due to high incidence of “0s” in data.