Table 3c.
Completer intake, final outcome, and change scores for subjective/objective primary and secondary measures, mean (95% confidence interval)a, for between mode (CPAP and ASV) comparison.
.
| Change between subjectsb | Between subjects (p-value, g) | |
|---|---|---|
| Primary measures | ||
| ISI | − 3.92 (− 7.70 to − 0.15) | 0.042, 0.65 |
| SQ-Lik | 0.58 (− 0.10 to 1.27) | 0.094, 0.54 |
| SQ-Pct (%) | 8.94 (− 1.85 to 19.72) | 0.101, 0.51 |
| Secondary measures | ||
| Questionnaires | ||
| ESS | − 0.49 (− 2.68 to 1.70) | 0.652, 0.14 |
| III | − 6.89 (− 11.92 to − 1.87) | 0.009, 0.88 |
| FSS | − 13.30 (− 20.20 to − 6.39) | 0.0004, 1.21 |
| FOSQ-10 | 1.67 (0.13–3.21)c | 0.030, 0.72c |
| QLESQ (%) | 10.71 (0.00–21.43)c | 0.034, 0.70c |
| Sleep diary | ||
| SOL | 0.58 (− 16.60 to 17.77)† | 0.946, 0.02 |
| WASO | 14.89 (− 23.29 to 53.06) | 0.434, 0.24 |
| SE (%) | 3.68 (− 11.55 to 4.19)† | 0.349, 0.29 |
| PSG sleep indices | ||
| SOL | 13.26 (− 36.62 to 10.10) | 0.257, 0.35 |
| WASO | 5.84 (− 32.90 to 44.59)† | 0.762, 0.10 |
| SE (%) | 3.61 (− 6.88 to 14.09) | 0.490, 0.22 |
| N1 (%) | 0.05 (− 4.08 to 3.99) | 0.981, 0.01 |
| N2 (%) | 0.75 (− 9.91 to 11.41)† | 0.887, 0.04 |
| N3 (%) | 1.64 (− 9.85 to 6.58)† | 0.689, 0.13 |
| REM (%) | 0.95 (− 4.34 to 6.24) | 0.718, 0.11 |
| REM (min) | 10.21 (− 11.27 to 31.69) | 0.341, 0.30 |
| REMCI | 0.48 (− 8.05 to 9.01) | 0.909, 0.04 |
| PSG breathing indices | ||
| AHI | 5.47 (− 5.24 to 16.18)† | 0.305, 0.31 |
| CAI | 0.18 (− 0.44 to 0.08) | 0.163, 0.46 |
| RDI | 1.88 (11.17–7.41) | 0.683, 0.13 |
| RERAI | 7.35 (− 3.01 to 17.70) | 0.157, 0.44 |
| NSBT (%) | 14.74 (− 2.62 to 32.10) | 0.094, 0.53 |
| NSBT (min) | 89.74 (29.38–150.11) | 0.005, 0.94 |
Abbreviations: ASV — adaptive servo-ventilation; CPAP — continuous positive airway pressure; ISI — Insomnia Severity Index; SQ-Lik — Sleep quality Likert scale; SQ-Pct — Sleep quality percent scale; ESS — Epworth Sleepiness Scale; III — Insomnia Impairment Index; FSS — Fatigue Severity Scale; FOSQ-10 — Functional Outcomes of Sleep Questionnaire Short Form; QLESQ — Quality of Life Enjoyment and Satisfaction Questionnaire Summary; SOL — sleep onset latency; WASO — wake after sleep onset; SE — sleep efficiency; N1 — non-REM stage 1; N2 — non-REM stage 2; N3 — non-REM stage 3; REM — rapid eye movement sleep; REMCI — REM consolidation index; AHI — Apnea Hypopnea Index; RDI — Respiratory Disturbance Index; RERAI — Respiratory Effort-Related Arousal event Index; OSA — obstructive sleep apnea; UARS — upper airway resistance syndrome; NSBT — normal sleep breathing time.
t-test confidence interval.
All improvements are as expected (greater improvement in ASV) except those identified by †.
Due to high prevalence of “0s” in data, Exact Wilcoxon Sign Ranked Test was used for pseudo median and confidence intervals.