Table 1.
IC50, µM |
|||
---|---|---|---|
Compound | LSD1 | MAO-A | MAO-B |
TCP | 2–100 | 0.48 | 4.881 |
RN-1 | 0.01–0.07 | 0.51 | 2.785 |
MAO, monoamine oxidase; RN-1, 2-(1R,2S)-2-{[4-(benzyloxy)phenyl]cyclopropylamino}-1-(4-methylpiperazin-1-yl)ethanone, HCl; TCP, tranylcypromine.