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. 2016 Nov 24;2016(11):CD004028. doi: 10.1002/14651858.CD004028.pub4

1.17. Analysis.

Comparison 1 VALPROATE + ANTIPSYCHOTICS versus ANTIPSYCHOTICS + PLACEBO or ANTIPSYCHOTICS alone, Outcome 17 Clinical response: 16. Aggression/Agitation: 5d. mean endpoint score PANSS‐EC subscale (skewed data).

Clinical response: 16. Aggression/Agitation: 5d. mean endpoint score PANSS‐EC subscale (skewed data)
Study Interventions Mean score SD N
Casey 2003 Valproate ‐ mean chlorprothixene dose ‐ high = poor ‐0.6 mg/d 1.48 122
Casey 2003 Placebo ‐ mean chlorprothixene dose ‐ high = poor ‐0.6 mg/d 1.27 120