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. 2016 Nov 24;2016(11):CD004028. doi: 10.1002/14651858.CD004028.pub4

1.23. Analysis.

Comparison 1 VALPROATE + ANTIPSYCHOTICS versus ANTIPSYCHOTICS + PLACEBO or ANTIPSYCHOTICS alone, Outcome 23 Use of additional medication: 1. Mean dose of antiparkinson medication (skewed data).

Use of additional medication: 1. Mean dose of antiparkinson medication (skewed data)
Study Interventions Mean score SD N
Dose 1998 Valproate ‐ mean biperiden dose ‐ high = poor 3.0 mg/d 2.4 14
Dose 1998 Placebo ‐ mean biperiden dose ‐ high = poor 2.4 mg/d 1.8 15
Hesslinger 1999 Valproate ‐ mean biperiden dose ‐ high = poor 3.6 mg/ 3.3 9
Hesslinger 1999 Placebo ‐ mean biperiden dose ‐ high = poor 2.9 mg/d 3 9