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. 2016 Nov 24;2016(11):CD004028. doi: 10.1002/14651858.CD004028.pub4

1.24. Analysis.

Comparison 1 VALPROATE + ANTIPSYCHOTICS versus ANTIPSYCHOTICS + PLACEBO or ANTIPSYCHOTICS alone, Outcome 24 Use of additional medication: 2. Mean chlorprothixene dose (skewed data).

Use of additional medication: 2. Mean chlorprothixene dose (skewed data)
Study Interventions Mean score SD N
Dose 1998 Valproate ‐ mean chlorprothixene dose ‐ high = poor 11.8 mg/d 13.4 14
Dose 1998 Placebo ‐ mean chlorprothixene dose ‐ high = poor 21.0 mg/d 25.4 15
Hesslinger 1999 Valproate ‐ mean chlorprothixene dose ‐ high = poor 21.1 mg/d 6.7 9
Hesslinger 1999 Placebo ‐ mean chlorprothixene dose ‐ high = poor 21.6 mg/d 17.4 9