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. 2019 Sep 3;10:2049. doi: 10.3389/fmicb.2019.02049

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Copyright © 2019 Mion, Rémy, Plener, Brégeon, Chabrière and Daudé.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of SsoPox-W263I on virulence factors of phage resistant mutants (gray) and the associated parental strains (black) in vitro. For each strain, bars represent the mean of protease (A), elastase (B), pyocyanin (C) and biofilm (D) levels of three experiments for treated culture with 0.5 mg ml^–¹ SsoPox-W263I (striped bar) or inactive mutant 5A8 as negative control (empty bar). ND: not detected. Error bars represent the standard deviations of three experiments. ^∗p-values < 0.05; ^∗∗p-values < 0.01; ^∗∗∗p-values < 0.001 according to Student’s t-test.