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. 2019 Sep 3;10:2049. doi: 10.3389/fmicb.2019.02049

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Copyright © 2019 Mion, Rémy, Plener, Brégeon, Chabrière and Daudé.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Combinatory effect of SsoPox-W263I and isolated phage on the virulence of PA14 and its phage resistant mutant against A. polyphaga Linc AP1. For each strain, curves represent the mean diameter of amoeba at different days after incubation in presence of bacteria without treatment (red) or treated with 10⁷ PFU ml^–1 ΦIntesti-PA14 (orange), 10 μg ml^–1 SsoPox-W263I (blue), or 10 μg ml^–1 SsoPox-W263I and 10⁷ PFU ml^–1 ΦIntesti-PA14 (green). Error bars represent the standard deviations of three experiments.