Table 5.

Longitudinal CSA reduction (ΔCSA, in mm²/month) for the ALS C9– patients, stratified for site of onset, compared to their matched controls.

		ΔCSA	p-value	FDR-corrected p-value
Bulbar vs CON	UCSC	0.004	0.344	0.746
	C1	0.002	0.739	0.746
	C2	0.001	0.741	0.746
	C3	0.011	0.048	0.237
	C4	0.003	0.746	0.746
Spinal vs CON	UCSC	0.004	0.005	0.026
	C1	0.003	0.122	0.153
	C2	0.005	0.012	0.027
	C3	0.005	0.016	0.027
	C4	<0.001	0.991	0.991
Bulbar vs spinal	UCSC	0.001	0.925	–
	C1	0.002	0.674	–
	C2	0.004	0.893	–
	C3	0.006	0.522	–
	C4	0.001	0.941	–