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Pain freedom occurred at similar time points in patients using versus not using preventive medications. Patients using (2a) and not using (2b) migraine preventive medications treated a migraine attack with lasmiditan (LTN) 50 mg, 100 mg, or 200 mg of or placebo (PBO). They then rated their pain at 0.5, 1, 1.5, and 2 h postdose. The percentages of patients reporting no pain at each time point are shown in the graph. *p < 0.05 compared to PBO, **p < 0.001 compared with PBO
