Table 3.
Diffusion characteristics for 3 major cerebellar tracts in the MWoA and healthy controls.
| L-SCP | R-SCP | L-MCP | R-MCP | L-ICP | R-ICP | |
|---|---|---|---|---|---|---|
| AD | ||||||
| HC | 0.92±0.14 | 0.91±0.14 | 0.83±0.12 | 0.86±0.12 | 0.90±0.14 | 0.89±0.14 |
| MWoA | 0.94±0.10 | 0.96±0.10 | 0.81±0.08 | 0.84±0.08 | 0.96±0.10 | 0.97±0.11 |
| P value | 0.590 | 0.069 | 0.324 | 0.462 | 0.045 | 0.002* |
| MD | ||||||
| HC | 0.63±0.11 | 0.62±0.10 | 0.57±0.14 | 0.59±0.13 | 0.70±0.12 | 0.69±0.11 |
| MWoA | 0.63±0.07 | 0.66±0.08 | 0.52±0.05 | 0.55±0.05 | 0.75±0.08 | 0.76±0.09 |
| P value | 0.997 | 0.072 | 0.032 | 0.044 | 0.057 | 0.001* |
| RD | ||||||
| HC | 0.48±0.10 | 0.48±0.09 | 0.44±0.15 | 0.45±0.15 | 0.60±0.11 | 0.59±0.10 |
| MWoA | 0.47±0.06 | 0.51±0.07 | 0.38±0.04 | 0.40±0.04 | 0.64±0.07 | 0.65±0.08 |
| P value | 0.694 | 0.094 | 0.013 | 0.015 | 0.079 | 0.001* |
| FA | ||||||
| HC | 0.30±0.06 | 0.30±0.05 | 0.37±0.12 | 0.37±0.12 | 0.22±0.05 | 0.21±0.05 |
| MWoA | 0.31±0.04 | 0.31±0.04 | 0.41±0.05 | 0.41±0.05 | 0.23±0.03 | 0.23±0.03 |
| P value | 0.157 | 0.162 | 0.012 | 0.011 | 0.094 | 0.125 |
AD Axial diffusivity, MD Mean diffusivity, RD Radial diffusivity, FA Fractional anisotropy, SCP Superior cerebellar peduncle, MCP Middle cerebellar peduncle, ICP Inferior cerebellar peduncle, * Statistical significance was set at p<0.0083, (Bonferroni corrected p<0.05). The MD, RD, and AD metrics are shown as 10-3, and FA is shown as the actual value. Note that only the right inferior cerebellar peduncle displayed significant increases in MD, RD, and AD compared with controls.