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. 2019 Sep 9;17:116. doi: 10.1186/s12964-019-0433-4

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Distribution of VEPH1 transcripts in human tissue and VEPH1 protein levels in established cell lines. a VEPH1 transcripts in human tissues reported in the human protein atlas (HPA) RNA dataset (proteinatlas.org). b VEPH1 protein levels expressed by various human cancer cell lines and non-malignant cell lines indicated by western blotting. Red = ovarian cancer cells, blue = breast cancer cells, green = prostate cancer cells, OE-E6/E7 = immortalized fallopian tube epithelial cells, HUVEC = human umbilical vein endothelial cells, HEC1B = endometrial cancer cells, CRL2854 = immortalized prostate fibroblasts, NTERA2 = testicular cancer cells. Data shown for the six ovarian cancer cell lines replicate our previously reported findings [6]. c Differential phosphorylation states of VEPH1 as shown by PhosTag western blot analysis. Shown are two exposure levels (top and middle blots) and results of VEPH1-transfected SKOV3 cells (SK-Ve) treated with or without λ-phosphatase (lower blot)