Table 3.
Top 20 PPI network topology property scores
| Gene | Degree | Gene | Betweenness | Gene | Closeness |
|---|---|---|---|---|---|
| CDC20 | 30 | HSPA8 | 18026.846 | CLTC | 0.009112669 |
| HSPA8 | 29 | RXRA | 15975.44 | MYC | 0.009111905 |
| CCNB2 | 25 | MAPK14 | 13874.259 | TFRC | 0.009106359 |
| BUB1 | 23 | MYC | 12210.541 | MAPK14 | 0.009104831 |
| KIF11 | 22 | CLTC | 10207.014 | CCNA2 | 0.009104831 |
| KIF20A | 22 | TFRC | 9083.066 | RB1 | 0.00910025 |
| CCNA2 | 22 | DVL2 | 8572.19 | SH3GL2 | 0.009099677 |
| HIST1H2BD | 21 | CCNA2 | 8557.233 | CEBPB | 0.009098914 |
| HIST1H2BN | 20 | MAP3K1 | 7784.2114 | HIST1H2BD | 0.009098342 |
| CLTC | 19 | COL1A2 | 7332.0977 | PRKACA | 0.009098151 |
| TFRC | 19 | PRKACA | 7097.15 | HIST1H2BN | 0.009098151 |
| DVL2 | 18 | NAPA | 6623.3286 | HSPA8 | 0.009097007 |
| PRKACA | 18 | HIST1H2BD | 6509.3853 | DVL2 | 0.009096816 |
| CDCA8 | 17 | CDC20 | 6327.5425 | PRKACB | 0.009096434 |
| NAPA | 17 | NCAM1 | 6277.285 | CEBPA | 0.009096053 |
| RACGAP1 | 17 | PRKACB | 6150.9224 | SLC2A4 | 0.009095863 |
| PPP2R5D | 16 | COL4A5 | 6065.6426 | RXRA | 0.009095673 |
| DYNC1I2 | 16 | L1CAM | 5992.727 | PSMC1 | 0.00909491 |
| B9D2 | 16 | HMGCS1 | 5969.1714 | KIF4A | 0.009094719 |
| SH3GL2 | 16 | HIST1H2BN | 5857.3853 | PSMB10 | 0.009094338 |